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  <titleInfo>
    <title>Bioinformatics and drug discovery</title>
  </titleInfo>
  <name type="personal">
    <namePart>Larson, Richard S.</namePart>
  </name>
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    <place>
      <placeTerm type="text">Totowa, N.J</placeTerm>
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    <publisher>Humana Press</publisher>
    <dateIssued>c2005</dateIssued>
    <dateIssued encoding="marc">2006</dateIssued>
    <issuance>monographic</issuance>
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    <languageTerm authority="iso639-2b" type="code">eng</languageTerm>
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    <extent>x, 444 p. : ill. ; 24 cm.</extent>
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  <tableOfContents>New strategies in drug discovery / Eliot H. Ohlstein ... [et al.] -- Basic microarray analysis : strategies for successful experiments / Scott A. Ness -- From microarray to biological networks : analysis of gene expression profiles / Xiwei Wu and T. Gregory Dewey -- Microarray analysis in drug discovery and clinical applications / Siqun Wang and Qiong Cheng -- Ontology-driven approaches to analyzing data in functional genomics / Francisco Azuje, Fatima Al-Shahrour, and Joaquin Dopazo -- Gene evolution and drug discovery / James O. McInerney ... [et al.] -- Standardization of microarray and pharmacogenomics data / Cassey S. Husser ... [et al.] -- Clinical applications of bioinformatics, genomics, and pharmacogenomics / Omer Iqbal --</tableOfContents>
  <tableOfContents>Protein interactions probed with mass spectrometry / Suma Kaveti and John R. Engen -- Discovering new drug targeting sites on flexible multidomain protein kinases : -- Combining segmental isotopic and site-directed spin labeling for NMR dectection of interfacial clefts / Thomas K. Harris -- NMR-based screening methods for drug discovery / Laurel Sillerud and Richard S. Larson -- Receptor binding sites : bioinformatic approaches / Darren R. Flower -- In silico protein design : fitting sequence onto structure / Bassil I. Dahiyat -- Chemical database preparation for compound acquisition or virtual screening / Cristian G. Bolgna, Marius M. Olah, and Tudor I. Oprea -- Bioinformatics platform development : from gene to lead compound / Alexis S. Ivanov ... [et al.].</tableOfContents>
  <note type="statement of responsibility">edited by Richard S. Larson.</note>
  <note>Includes bibliographical references and index.</note>
  <subject authority="lcsh">
    <topic>Drug development</topic>
  </subject>
  <subject authority="lcsh">
    <topic>Bioinformatics</topic>
  </subject>
  <subject authority="lcsh">
    <topic>High throughput screening (Drug development)</topic>
  </subject>
  <subject authority="lcsh">
    <topic>Combinatorial chemistry</topic>
  </subject>
  <subject authority="mesh">
    <topic>Drug Design</topic>
  </subject>
  <subject authority="mesh">
    <topic>Computational Biology</topic>
    <topic>methods</topic>
  </subject>
  <subject authority="mesh">
    <topic>Drug Evaluation, Preclinical</topic>
  </subject>
  <subject authority="mesh">
    <topic>Genetic Techniques</topic>
  </subject>
  <subject authority="mesh">
    <topic>Microarray Analysis</topic>
  </subject>
  <subject authority="mesh">
    <topic>Pharmacogenetics</topic>
    <topic>methods</topic>
  </subject>
  <classification authority="ddc" edition="22">615.19 BIO 2006</classification>
  <classification authority="nlm">W1 ME9616J v.316 2005</classification>
  <classification authority="nlm">QV 744 B6136 2005</classification>
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      <title>v. 316</title>
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    <titleInfo>
      <title>Methods in molecular biology (Clifton, N.J.)</title>
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  <identifier type="isbn">1588293467 (alk. paper)</identifier>
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